{{immunebox
| Name        =<b> Chromosomal replication Initiation Protein</b>
|image=
| width=250
|image2=
|Swiss Prot =  P49993
| Genbank          = 885041
| PDB         = not available	
| molecular_weight  = 56548.6

| solubility        = 
|Isoelectric-Point = 5.45
}}
=General=
Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids 
=Amino Acid Sequence of Rv0001=
>>Rv0001, TB.seq  1:1521 MW:56550 
LTDDPGSGFTTVWNAVVSELNGDPKVDDGPSSDANLSAPLTPQQRAWLNLVQPLTIVEGFALLSVPSSFVQNEIERHLRA
PITDALSRRLGHQIQLGVRIAPPATDEADDTTVPPSENPATTSPDTTTDNDEIDDSAAARGDNQHSWPSYFTERPHNTDS
ATAGVTSLNRRYTFDTFVIGASNRFAHAAALAIAEAPARAYNPLFIWGESGLGKTHLLHAAGNYAQRLFPGMRVKYVSTE
EFTNDFINSLRDDRKVAFKRSYRDVDVLLVDDIQFIEGKEGIQEEFFHTFNTLHNANKQIVISSDRPPKQLATLEDRLRT
RFEWGLITDVQPPELETRIAILRKKAQMERLAVPDDVLELIASSIERNIRELEGALIRVTAFASLNKTPIDKALAEIVLR
DLIADANTMQISAATIMAATAEYFDTTVEELRGPGKTRALAQSRQIAMYLCRELTDLSLPKIGQAFGRDHTTVMYAQRKI
LSEMAERREVFDHVKELTTRIRQRSKR
*
=Tertiary Structure=
This protein structure is not available in PDB. 
==Structure Prediction==
Tertiary structure is predicted using Homology modeling - Modbase  (http://modbase.compbio.ucsf.edu/modbase-cgi/model_details.cgi?queryfile=1265611304_5192&searchmode=default&displaymode=moddetail&referer=yes&snpflag=&)

  

= Structure Classification =

==Secondray Structure==


==Secondary Structure Prediction==
  Secondary structure of this protein is predicted using GOR 
=Related Publications=
[[Category:C2D]]
[[Category:Mtb Station]]