Mechanistic Toxicology

From DrugPedia: A Wikipedia for Drug discovery

[edit] definition

Is a branch of Toxicology, which focuses on

• Chemicals produce adverse effects
• Biological systems protect themselves against adverse effects

Chemical research in toxicology usually investigates metabolic transformations of drugs or potentially hazardous chemicals.

Involves

• Cellular and Molecular Biology
• Chemistry, often xenobiotic metabolism

[edit] Questions asked by Mechanistic Toxicologist

• How persistent is a chemical in the body?
• Are metabolic products toxic?
• Do test animals exhibit the same results as humans or other species of concern?

Society of Toxicology