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  • Entrez
    *''Nucleotide'': sequence database ([[GenBank]]) *''SNP'': single nucleotide polymorphism
    5 KB (692 words) - 04:33, 17 August 2008
  • Chemical file format
    <td>chemical/x-embl-dl-nucleotide</td> <td>EMBL Nucleotide Format</td>
    14 KB (2238 words) - 09:36, 17 September 2008
  • Protein structure
    ... ermined by the gene corresponding to the protein. A specific sequence of [[nucleotide]]s in [[DNA]] is [[Transcription (genetics)|transcribed]] into [[mRNA]], w ...
    27 KB (4092 words) - 12:18, 4 December 2008
  • DNA
    Chemically, DNA consists of two long [[polymers]] of simple units called [[nucleotide]]s, with backbones made of sugars and phosphate groups joined by [[ester] ... ... very small, DNA polymers can be enormous molecules containing millions of nucleotides. For instance, the largest human chromosome, chromosome number 1, is appr ...
    82 KB (11827 words) - 06:08, 20 August 2008
  • Protein Data Bank
    ... d]], the much larger databases from [[Swiss-Prot]] and the [[International Nucleotide Sequence Database Collaboration]] should be used.
    11 KB (1705 words) - 05:34, 19 August 2008
  • BLAST
    ... mino-acid]] sequences of different [[Protein structure|proteins]] or the [[nucleotide]]s of [[DNA sequence]]s. A ''BLAST search'' enables a researcher to compar ... ... uery may be one thousand nucleotides while the database is several billion nucleotides.
    20 KB (3062 words) - 11:25, 19 August 2008
  • FASTA
    ... works with any alphabet, an extension of "FAST-P" (protein) and "FAST-N" (nucleotide) alignment. ... hich six-frame-translated searches do not handle very well) when comparing nucleotide to protein sequence data.
    9 KB (1295 words) - 11:59, 19 August 2008
  • RNA
    ... RNA is usually single stranded, while DNA is usually double stranded. RNA nucleotides contain ribose while DNA contains [[deoxyribose]] (a type of ribose that ... Each nucleotide in RNA contains a ribose sugar, with carbons numbered 1' through 5'. A bas ...
    31 KB (4467 words) - 07:24, 20 August 2008
  • Pharmacogenomics
    ... n drug response in patients by correlating [[gene expression]] or [[single-nucleotide polymorphism]]s with a drug's [[efficacy]] or [[toxicity]]. By doing so, ...
    2 KB (269 words) - 11:36, 20 August 2008
  • PRRDB, pattern-recognition receptor
    ... e DC-SIGN receptors, 43 are Peptidoglycan recognition receptors and 67 are Nucleotide binding site-Leucine rich repeats rich receptors. Information about the PR ...
    3 KB (407 words) - 04:15, 22 August 2008
  • Bioinformatics and Drug discovery
    ... nown that a drug must bind to a particular spot on a particular protein or nucleotide then a drug can be tailor made to bind at that site. This is often modeled ...
    9 KB (1370 words) - 07:16, 26 August 2008
  • Secondary structure prediction
    ... sed only on knowledge of their [[primary structure]] - [[amino acid]] or [[nucleotide]] sequence, respectively. For proteins, a prediction consists of assignin ... ... ion]]; maintenance at two widely separated sites of a pair of base-pairing nucleotides indicates the presence of a structurally required hydrogen bond between t ...
    12 KB (1607 words) - 06:13, 27 August 2008
  • Datasets in Bioinformatics
    All data were taken from the GenBank collection of human nucleotide sequence data on May 30, 1992. All E. coli sequences were extracted on Jun ... ... ern (nucleotides having cleavage site at center) and non-cleavage pattern (nucleotides having no cleavage site) from 719 experimentally validated miRNA obtained ...
    16 KB (2424 words) - 11:41, 5 September 2008
  • List of Phylogenetic Softwares
    | Optimized maximum likelihood (nucleotides only) || Maximum likelihood || [http://geta.life.uiuc.edu/~gary/programs/ ... | Molecular phylogenetics (protein or nucleotide) || Maximum likelihood || [http://bioweb.pasteur.fr/seqanal/interfaces/pro ...
    8 KB (1003 words) - 05:02, 4 September 2008
  • SNP
    ... ividuals, AAGC'''C'''TA to AAGC'''T'''TA, contain a difference in a single nucleotide. In this case we say that there are two ''alleles'' : C and T. Almost all ... This is simply the lesser of the two allele frequencies for single nucleotide polymorphisms.
    6 KB (930 words) - 08:53, 16 September 2008
  • Bioconductor
    ... f genomic data, such as SAGE, [[Sequence (biology)|sequence]], or [[Single nucleotide polymorphism|SNP]] data.
    12 KB (1522 words) - 04:17, 9 September 2008
  • GenBank
    ... new release is made every two months. GenBank is part of the International Nucleotide Sequence Database Collaboration, which comprises the DNA DataBank of Japan ...
    3 KB (426 words) - 04:26, 9 September 2008
  • Site directed mutagenesis
    ... lones can be screened by nucleic acid hybridization with 32P- labeled oligonucleotide as probe. Under suitable stringent conditions i.e. temperature and cation ... ... . The reaction essentially replicates the dUTP-containing plasmid the oligonucleotide as primer, giving a nearly identical copy. The essential differences being ...
    12 KB (1824 words) - 05:04, 9 September 2008
  • SDS PAGE
    ... at higher concentrations, is used to separate most proteins and small oligonucleotides that require a small gel pore size for retardation. ... tive charge per unit length of molecule, provided by the PO4 group of each nucleotide of the the nucleic acid. Electrophoretic separation of nucleic acids there ...
    5 KB (809 words) - 05:30, 9 September 2008
  • Phylogenetic analysis
    ... ive organisms, while the more recent field of molecular phylogenetics uses nucleotide sequences encoding genes or amino acid sequences encoding proteins as the ... ... n biological sequence data are immediate and discretely defined - distinct nucleotides in DNA or RNA sequences and distinct amino acids in protein sequences. Ho ...
    25 KB (3849 words) - 07:10, 9 September 2008

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