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Temafloxacin (marketed by Abbott Laboratories as Omniflox), is a fluoroquinolone antibiotic drug which was withdrawn from sale in the U.S. shortly after its approval in 1992 because of serious adverse reactions resulting in three deaths.

Omniflox was approved to treat lower respiratory tract infections, genital and urinary infections <span class="plainlinks">[http://xcellulite.com <span style="color:black;font-weight:normal;text-decoration:none!important;background:none!important; text-decoration:none;">cellulite removal</span>]</span> like prostatitis, and skin infections in the U.S. by the Food and Drug Administration in January 1992. Severe adverse reactions, including allergic reactions and hemolytic anemia, developed in about fifty patients during the first four months of its use, leading to three patient deaths. Abbott withdrew the drug from sale in June 1992.