Rv0014c

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|Swiss Prot =  P0A5S4  
|Swiss Prot =  P0A5S4  
| Genbank          = 887072
| Genbank          = 887072
-
| PDB        =  3F61, 3F69, 2FUM, 1MRU, 1O6Y
+
| PDB        =  3F61
| DrugBank          =
| DrugBank          =
| chemical_formula  = C21H33NO2  [http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=887072&loc=ec_rcs]
| chemical_formula  = C21H33NO2  [http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=887072&loc=ec_rcs]
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=General=
=General=
INVOLVED IN SIGNAL TRANSDUCTION (VIA PHOSPHORYLATION). THOUGHT TO REGULATE CELL DIVISION/DIFFERENTIATION. CAN PHOSPHORYLATE THE PEPTIDE SUBSTRATE MYELIN BASIC PROTEIN (MBP) [CATALYTIC ACTIVITY: ATP + A PROTEIN = ADP + A PHOSPHOPROTEIN].   
INVOLVED IN SIGNAL TRANSDUCTION (VIA PHOSPHORYLATION). THOUGHT TO REGULATE CELL DIVISION/DIFFERENTIATION. CAN PHOSPHORYLATE THE PEPTIDE SUBSTRATE MYELIN BASIC PROTEIN (MBP) [CATALYTIC ACTIVITY: ATP + A PROTEIN = ADP + A PHOSPHOPROTEIN].   
 +
 +
Other PDBID: 3F69, 2FUM, 1MRU, 1O6Y
==Protein Sequence==
==Protein Sequence==

Revision as of 11:54, 3 February 2010

Rv0014c
Name
Serine/threonine-protein kinase pknB
Identifiers
Swiss Prot P0A5S4
Genbank 887072
PDB 3F61
Chemical data
Formula C21H33NO2 [1]
Mol. wt. 66511 Da
Pharmacokinetic data
Bioavailability  ?
Solubility  ?
Isoelectric-Point 5.08

Contents

General

INVOLVED IN SIGNAL TRANSDUCTION (VIA PHOSPHORYLATION). THOUGHT TO REGULATE CELL DIVISION/DIFFERENTIATION. CAN PHOSPHORYLATE THE PEPTIDE SUBSTRATE MYELIN BASIC PROTEIN (MBP) [CATALYTIC ACTIVITY: ATP + A PROTEIN = ADP + A PHOSPHOPROTEIN].

Other PDBID: 3F69, 2FUM, 1MRU, 1O6Y

Protein Sequence

>Rv0014c, TB.seq 15593:17470 MW:66511 MTTPSHLSDRYELGEILGFGGMSEVHLARDLRLHRDVAVKVLRADLARDPSFYLRFRREAQNAAALNHPAIVAVYDTGEA ETPAGPLPYIVMEYVDGVTLRDIVHTEGPMTPKRAIEVIADACQALNFSHQNGIIHRDVKPANIMISATNAVKVMDFGIA RAIADSGNSVTQTAAVIGTAQYLSPEQARGDSVDARSDVYSLGCVLYEVLTGEPPFTGDSPVSVAYQHVREDPIPPSARH EGLSADLDAVVLKALAKNPENRYQTAAEMRADLVRVHNGEPPEAPKVLTDAERTSLLSSAAGNLSGPRTDPLPRQDLDDT DRDRSIGSVGRWVAVVAVLAVLTVVVTIAINTFGGITRDVQVPDVRGQSSADAIATLQNRGFKIRTLQKPDSTIPPDHVI GTDPAANTSVSAGDEITVNVSTGPEQREIPDVSTLTYAEAVKKLTAAGFGRFKQANSPSTPELVGKVIGTNPPANQTSAI TNVVIIIVGSGPATKDIPDVAGQTVDVAQKNLNVYGFTKFSQASVDSPRPAGEVTGTNPPAGTTVPVDSVIELQVSKGNQ FVMPDLSGMFWVDAEPRLRALGWTGMLDKGADVDAGGSQHNRVVYQNPPAGTGVNRDGIITLRFGQ


Human Homologue Blast Result

subject ids% identity% positivesalignment length evalue

Alergen Protein

Link to Algpred
Non Allergen Predicted by AlgPred Server

Bacterial Toxin Prediction

Link to btxpred
No Hit Fountd by btxpred server.

Subcellular Location

Link to TBpred
Integral Membrane

Antigens

No Hit Found in AntigenDB
No. Hit Found in IEDB

B cell Epitopes

BCEpred Analysis

Link to Bcepred
Result Predicited by

ABCpred Analysis

Link to ABCpred
Result Predicited by

IEDB Analysis

Link to IEDB
Result Predicited by

MHC Class-I Binder

nHLAPred Analysis

Link to nHLApred
Result Predicited by

IEDB Analysis

Link to IEDB
Result Predicted by

MHC Class-II Binder

Propred Analysis

Link to Propred
Result Predicted by


NetMHC-II Analysis

Link to NetMHC-II
Result Predicted by

External Links

  • Database of Mycobacterium tuberculosis genome sequences and related information.