20-Hydroxyecdysone
From DrugPedia: A Wikipedia for Drug discovery
(Difference between revisions)
(New page: '''Ecdysterone''' Pubchem(5459840,3032482) A steroid hormone that regulates the processes of MOLTING or ecdysis in insects. Ecdysterone is the 20-hydroxylated ECDYSONE. '''KEGG Pathway'...) |
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| + | ! style="background:brown; color:white" |Organism | ||
| + | ! style="background:brown; color:white" |Test Type | ||
| + | ! style="background:brown; color:white" |Route | ||
| + | ! style="background:brown; color:white" |Reported Dose (Normalized Dose) | ||
| + | ! style="background:brown; color:white" |Effect | ||
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|mouse | |mouse | ||
|LD50 | |LD50 | ||
|intraperitoneal | |intraperitoneal | ||
| - | |6400mg/kg (6400mg/kg) | + | |6400mg/kg (6400mg/kg) |
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|Nippon Yakurigaku Zasshi. Japanese Journal of Pharmacology. Vol. 66, Pg. 551, 1970. | |Nippon Yakurigaku Zasshi. Japanese Journal of Pharmacology. Vol. 66, Pg. 551, 1970. | ||
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|LD50 | |LD50 | ||
|oral | |oral | ||
| - | |> 9gm/kg (9000mg/kg) | + | |> 9gm/kg (9000mg/kg) |
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|Nippon Yakurigaku Zasshi. Japanese Journal of Pharmacology. Vol. 66, Pg. 551, 1970. | |Nippon Yakurigaku Zasshi. Japanese Journal of Pharmacology. Vol. 66, Pg. 551, 1970. | ||
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Revision as of 04:59, 3 November 2008
Ecdysterone
Pubchem(5459840,3032482)
A steroid hormone that regulates the processes of MOLTING or ecdysis in insects. Ecdysterone is the 20-hydroxylated ECDYSONE.
KEGG Pathway(C02633)
- Insect hormone biosynthesis
|59627 |2R40 |Browning C, Martin E, Loch C, Wurtz JM, Moras D, Stote RH, Dejaegere AP, Billas IMCritical Role of Desolvation in the Binding of 20-Hydroxyecdysone to the Ecdysone ReceptorJ. Biol. Chem. v282, p.32924-32934 |- |}
| Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
|---|---|---|---|---|---|
| mouse | LD50 | intraperitoneal | 6400mg/kg (6400mg/kg) | Nippon Yakurigaku Zasshi. Japanese Journal of Pharmacology. Vol. 66, Pg. 551, 1970. | |
| mouse | LD50 | oral | > 9gm/kg (9000mg/kg) | Nippon Yakurigaku Zasshi. Japanese Journal of Pharmacology. Vol. 66, Pg. 551, 1970. |
