Cryptococcus neoformans
From DrugPedia: A Wikipedia for Drug discovery
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'''Cryptococcus neoformans''' | '''Cryptococcus neoformans''' | ||
+ | It is an encapsulated yeast that can live in both plants and animals. Its teleomorph is Filobasidiella neoformans, a filamentous fungus belonging to the class Tremellomycetes. | ||
+ | {| border="1" style="text-align: left;" | ||
+ | |+ '''Scientific classification''' | ||
+ | !Kingdom || Fungi | ||
+ | |- | ||
+ | ! Phylum || Basidiomycota | ||
+ | |- | ||
+ | ! Class || Tremellomycetes | ||
+ | |- | ||
+ | ! Order || Tremellales | ||
+ | |- | ||
+ | ! Family || Tremellaceae | ||
+ | |- | ||
+ | ! Genus || Cryptococcus | ||
+ | |- | ||
+ | ! Species || '''''C. neoformans''''' | ||
+ | |- | ||
+ | ! Binomial || ''Cryptococcus neoformans'' | ||
+ | |} | ||
+ | ==Surface Characteristics== | ||
+ | The cell wall contains a linear (1-->3)-linked mannan backbone singly substituted with nonreducing β(1-->2) xylose and β(1-->2) glucuronic acid side branches ; O-acetyl groups are present at C-6 of the mannosyl residues. | ||
+ | ==Pathogenic Activity== | ||
+ | Infection with C. neoformans is termed cryptococcosis. Most infections with C. neoformans consist of a lung infection. However, fungal meningitis, especially as a secondary infection for AIDS patients, is often caused by C. neoformans making it a particularly dangerous fungus. Infections with this fungus are rare in those with fully functioning immune systems. For this reason, C. neoformans is sometimes referred to as an opportunistic fungus. | ||
+ | ==References== | ||
+ | [http://en.wikipedia.org/wiki/Cryptococcus_neoformans Wikipedia] | ||
- | + | [[category: PolysacDB]] | |
- | + | ||
- | [[category: | + |
Current revision
Cryptococcus neoformans
It is an encapsulated yeast that can live in both plants and animals. Its teleomorph is Filobasidiella neoformans, a filamentous fungus belonging to the class Tremellomycetes.
Kingdom | Fungi |
---|---|
Phylum | Basidiomycota |
Class | Tremellomycetes |
Order | Tremellales |
Family | Tremellaceae |
Genus | Cryptococcus |
Species | C. neoformans |
Binomial | Cryptococcus neoformans |
[edit] Surface Characteristics
The cell wall contains a linear (1-->3)-linked mannan backbone singly substituted with nonreducing β(1-->2) xylose and β(1-->2) glucuronic acid side branches ; O-acetyl groups are present at C-6 of the mannosyl residues.
[edit] Pathogenic Activity
Infection with C. neoformans is termed cryptococcosis. Most infections with C. neoformans consist of a lung infection. However, fungal meningitis, especially as a secondary infection for AIDS patients, is often caused by C. neoformans making it a particularly dangerous fungus. Infections with this fungus are rare in those with fully functioning immune systems. For this reason, C. neoformans is sometimes referred to as an opportunistic fungus.