Glaucine
From DrugPedia: A Wikipedia for Drug discovery
(Difference between revisions)
m |
(→Description) |
||
(One intermediate revision not shown.) | |||
Line 24: | Line 24: | ||
==Description== | ==Description== | ||
+ | |||
RN given refers to (+-)-isomer | RN given refers to (+-)-isomer | ||
+ | |||
+ | Glaucine is an alkaloid found in several different plant species such as Glaucium flavum, Glaucium oxylobum, Croton lechleri and Corydalis yanhusuo. It has bronchodilator and antiinflammatory effects, acting as a PDE4 inhibitor and calcium channel blocker, and is used medically as an antitussive in some countries. Glaucine may produce side effects such as sedation, fatigue, and a hallucinogenic effect characterised by colourful visual images, and has recently been detected as a novel recreational drug. | ||
==General Properties== | ==General Properties== |
Current revision
Glaucine
| |
Systematic (IUPAC) name | |
N/A | |
Identifiers | |
CAS number | ? |
ATC code | ? |
PubChem | |
Chemical data | |
Formula | C21H25NO4 |
Mol. mass | 355.4275 |
SMILES | & |
Pharmacokinetic data | |
Bioavailability | ? |
Metabolism | ? |
Half life | ? |
Excretion | ? |
Therapeutic considerations | |
Pregnancy cat. |
? |
Legal status | |
Routes | ? |
[edit] Description
RN given refers to (+-)-isomer
Glaucine is an alkaloid found in several different plant species such as Glaucium flavum, Glaucium oxylobum, Croton lechleri and Corydalis yanhusuo. It has bronchodilator and antiinflammatory effects, acting as a PDE4 inhibitor and calcium channel blocker, and is used medically as an antitussive in some countries. Glaucine may produce side effects such as sedation, fatigue, and a hallucinogenic effect characterised by colourful visual images, and has recently been detected as a novel recreational drug.
[edit] General Properties
*Molecular Weight
355.4275
*Molecular Formula
C21H25NO4
*IUPAC NAME
N/A
*Canonical Smiles
CN1CCC2=CC(=C(C3=C2C1CC4=CC(=C(C=C43)OC)OC)OC)OC
*Isomeric Smiles
N/A
*XLogP
2.6
*Topological Polar Surface Area
40.2