PolysacDB Mycolyl-arabinogalactan-peptidoglycan complex 1008
From DrugPedia: A Wikipedia for Drug discovery
(Difference between revisions)
m (1 revision) |
m (1 revision) |
Current revision
[edit] Carbohydrate Name
Mycolyl-arabinogalactan-peptidoglycan complex
[edit] Carbohydrate Class
Miscellaneous
[edit] Source Microbe
Mycobacterium tuberculosis
[edit] Basic Structure
Mycolyl-arabinogalactan-peptidoglycan complex is the fraction of the mycobacterial cell wall left after removing all soluble carbohydrates, proteins and lipids
[edit] Proposed functions
Contains lipoarabinomannan as well as arabinose that are important virulence factors
[edit] Antigenic Nature used to produce antibodies
Heat killed Mycobacterium tuberculosis
[edit] Carrier Name
nil
[edit] Conjugation Method
nil
[edit] Antibodies
Mabs 4f11
[edit] Antibody type and class
IgM
[edit] Assay System
Indirect immunofluorescence, ELISA, western blotting
[edit] Cross-reactivity
This antibody cross-reacted with large number of mycobacterial species.
[edit] Proposed epitopes
Arabinose moiety of Lipoarabinomannan
[edit] Proposed Utility
This antibody has been used in the detection of mycobacteria in clinical samples