Mestranol
From DrugPedia: A Wikipedia for Drug discovery
(Difference between revisions)
(New page: '''Mestranol''' Pubchem(6291) The 3-methyl ether of ETHINYL ESTRADIOL. It must be demethylated to be biologically active. It is used as the estrogen component of many combination ORAL CONT...) |
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'''Activity''' Estrogen | '''Activity''' Estrogen | ||
| - | + | {| border="1;width:100%; height:200px;style=text-align:center" | |
| - | Physical Property | + | |+'''Physiochemical properties of Estriol:''' |
| + | |- | ||
| + | ! style="background:brown; color:white" |Physical Property | ||
| + | ! style="background:brown; color:white" |Value | ||
| + | ! style="background:brown; color:white" |Units | ||
| + | ! style="background:brown; color:white" |Temp (deg C) | ||
| + | ! style="background:brown; color:white" |Source | ||
| + | |- | ||
|Melting Point | |Melting Point | ||
|150.5 | |150.5 | ||
Revision as of 06:51, 31 October 2008
Mestranol Pubchem(6291) The 3-methyl ether of ETHINYL ESTRADIOL. It must be demethylated to be biologically active. It is used as the estrogen component of many combination ORAL CONTRACEPTIVES.
KEGG(C07618,D00575)
Activity Estrogen
| Physical Property | Value | Units | Temp (deg C) | Source | |
|---|---|---|---|---|---|
| Melting Point | 150.5 | deg C | EXP | ||
| log P (octanol-water) | 4.680 | (none) | EST | ||
| Atmospheric OH Rate Constant | 9.04E-11 | cm3/molecule-sec | 25 | EST | |
| mouse | LD50 | intraperitoneal | > 3200mg/kg (3200mg/kg) | SENSE ORGANS AND SPECIAL SENSES: LACRIMATION: EYE
BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) SKIN AND APPENDAGES (SKIN): HAIR: OTHER | Oyo Yakuri. Pharmacometrics. Vol. 4, Pg. 217, 1970. |
| mouse | LD50 | oral | > 10gm/kg (10000mg/kg) | SENSE ORGANS AND SPECIAL SENSES: PTOSIS: EYE
BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) SKIN AND APPENDAGES (SKIN): HAIR: OTHER | Oyo Yakuri. Pharmacometrics. Vol. 4, Pg. 217, 1970. |
| mouse | LD50 | subcutaneous | 2500mg/kg (2500mg/kg) | SENSE ORGANS AND SPECIAL SENSES: LACRIMATION: EYE
SENSE ORGANS AND SPECIAL SENSES: PTOSIS: EYE SKIN AND APPENDAGES (SKIN): HAIR: OTHER | Oyo Yakuri. Pharmacometrics. Vol. 4, Pg. 217, 1970. |
| rat | LD50 | intraperitoneal | > 3gm/kg (3000mg/kg) | BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDS SKIN AND APPENDAGES (SKIN): HAIR: OTHER | Oyo Yakuri. Pharmacometrics. Vol. 4, Pg. 217, 1970. |
| rat | LD50 | oral | > 10gm/kg (10000mg/kg) | Oyo Yakuri. Pharmacometrics. Vol. 4, Pg. 217, 1970. | |
| rat | LD50 | subcutaneous | > 5gm/kg (5000mg/kg) | BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDS SKIN AND APPENDAGES (SKIN): HAIR: OTHER | Oyo Yakuri. Pharmacometrics. Vol. 4, Pg. 217, 1970. |
