Mechanistic Toxicology

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* Are [[metabolic]] products toxic?
* Are [[metabolic]] products toxic?
* Do test animals exhibit the same results as humans or other [[species]] of concern?
* Do test animals exhibit the same results as humans or other [[species]] of concern?
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[http://www.toxicology.org/ Society of Toxicology]

Current revision

[edit] definition

Is a branch of Toxicology, which focuses on

  • Chemicals produce adverse effects
  • Biological systems protect themselves against adverse effects

Chemical research in toxicology usually investigates metabolic transformations of drugs or potentially hazardous chemicals.

Involves

  • Cellular and Molecular Biology
  • Chemistry, often xenobiotic metabolism

[edit] Questions asked by Mechanistic Toxicologist

  • How persistent is a chemical in the body?
  • Are metabolic products toxic?
  • Do test animals exhibit the same results as humans or other species of concern?

Society of Toxicology