Melanotropin alpha 2
From DrugPedia: A Wikipedia for Drug discovery
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Revision as of 08:22, 13 February 2009
Contents |
Description
Corticotropin-lipotropin B precursor (Pro-opiomelanocortin B) (POMC B)[Contains: NPP 2; Corticotropin (Adrenocorticotropic hormone) (ACTH);Melanotropin alpha 2 (Alpha-MSH 2); Corticotropin-like intermediarypeptide 2 (CLIP-2); Lipotropin beta (Beta-LPH); Lipotropin gamma(Gamma-LPH); Melanotropin beta 2 (Beta-MSH 2); Beta-endorphin 2; Met-enkephalin].
Source Organism
Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri).
Taxomomy
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Euteleostei;Protacanthopterygii; Salmoniformes; Salmonidae; Oncorhynchus.
Subcellular Localization
Developmental Stage
Expressed only in sexually active fish.
Similarity
Belongs to the POMC family.
Post translational Modification
Specific enzymatic cleavages at paired basic residues yield the different active peptides. Acetylation of beta-endorphin occurs in a tissue-specific manner.
Function
GeneID
100136772