Diuretic hormone class 2
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Description
Diuretic hormone class 2 (Diuretic hormone class II) (Diureticpeptide) (DP) (DH(31)).
Source Organism
Diploptera punctata (Pacific beetle cockroach).
Taxomomy
Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota;Neoptera; Orthopteroidea; Dictyoptera; Blattaria; Blaberidae;Diplopterinae; Diploptera.
Subcellular Localization
Secreted protein.
Developmental Stage
Similarity
Belongs to the diuretic hormone class II family.
Post translational Modification
Function
Regulation of fluid secretion. Stimulates primary urine secretion by Malpighian tubules and causes a dose-dependent stimulation of cAMP levels in the tubules. Has a nonselective effect on Na(+)/K(+) ion transport. In vitro, primarily elevates intracellular Ca(2+). Has synergistic effects with the larger diuretic hormone DH(46) which co-occurs with it