From DrugPedia: A Wikipedia for Drug discovery

Revision as of 11:38, 6 February 2010 (edit) Nitinkumar (Talk | contribs) (→Human Homologue Blast Result) ← Previous diff		Revision as of 11:41, 6 February 2010 (edit) (undo) Nitinkumar (Talk | contribs) (→Subcellular Location) Next diff →
Line 55:		Line 55:
	=Subcellular Location=		=Subcellular Location=
	Link to [http://www.imtech.res.in/raghava/tbpred/ TBpred]<br>		Link to [http://www.imtech.res.in/raghava/tbpred/ TBpred]<br>
-	Integral Membrane	+	Cytoplasmic
	=Antigens=		=Antigens=

---

Revision as of 11:41, 6 February 2010

Rv3396c
Name
guaA
Identifiers
Swiss Prot	P0A5A1
Genbank	887412
PDB	?
Chemical data
Formula	C14H17ClN2O2 [1]
Mol. wt.	56029 Da
Pharmacokinetic data
Bioavailability	?
Solubility	?
Isoelectric-Point	5.2

Contents 1 General 1.1 Protein Sequence 2 Human Homologue Blast Result 3 Alergen Protein 4 Bacterial Toxin Prediction 5 Subcellular Location 6 Antigens 6.1 B cell Epitopes 6.1.1 BCEpred Analysis 6.1.2 ABCpred Analysis 6.1.3 IEDB Analysis 7 MHC Class-I Binder 7.1 nHLAPred Analysis 7.2 IEDB Analysis 8 MHC Class-II Binder 8.1 Propred Analysis 8.2 NetMHC-II Analysis 9 External Links

General

INVOLVED IN GMP BIOSYNTHESIS [CATALYTIC ACTIVITY: ATP + XANTHOSINE 5'-PHOSPHATE + L-GLUTAMINE + H(2)O = AMP + PYROPHOSPHATE + GMP + L-GLUTAMATE].

Protein Sequence

>Rv3396c, TB.seq 3812500:3814074 MW:56029 VVQPADIDVPETPARPVLVVDFGAQYAQLIARRVREARVFSEVIPHTASIEEIRARQPVALVLSGGPASVYADGAPKLDP ALLDLGVPVLGICYGFQAMAQALGGIVAHTGTREYGRTELKVLGGKLHSDLPEVQPVWMSHGDAVTAAPDGFDVVASSAG APVAAFEAFDRRLAGVQYHPEVMHTPHGQQVLSRFLHDFAGLGAQWTPANIANALIEQVRTQIGDGHAICGLSGGVDSAV AAALVQRAIGDRLTCVFVDHGLLRAGERAQVQRDFVAATGANLVTVDAAETFLEALSGVSAPEGKRKIIGRQFIRAFEGA VRDVLDGKTAEFLVQGTLYPDVVESGGGSGTANIKSHHNVGGLPDDLKFTLVEPLRLLFKDEVRAVGRELGLPEEIVARQ PFPGPGLGIRIVGEVTAKRLDTLRHADSIVREELTAAGLDNQIWQCPVVLLADVRSVGVQGDGRTYGHPIVLRPVSSEDA MTADWTRVPYEVLERISTRITNEVAEVNRVVLDITSKPPATIEWE

Human Homologue Blast Result

subject ids	% identity	% positives	alignment length	evalue
sp|P49915.1	35	51	546	2e-76
sp|O75648.2	55	76	34	0.032
sp|P55145.2	33	43	48	0.35
sp|P27708.3	30	45	104	1
sp|Q13576.3	23	42	76	1.4

Alergen Protein

Link to Algpred
Non Allergen Predicted by AlgPred Server

Bacterial Toxin Prediction

Link to btxpred
No Hit Fountd by btxpred server.

Subcellular Location

Link to TBpred
Cytoplasmic

Antigens

No Hit Found in AntigenDB
No. Hit Found in IEDB

B cell Epitopes

BCEpred Analysis

Link to Bcepred
Result Predicited by

ABCpred Analysis

Link to ABCpred
Result Predicited by

IEDB Analysis

Link to IEDB
Result Predicited by

MHC Class-I Binder

nHLAPred Analysis

Link to nHLApred
Result Predicited by

IEDB Analysis

Link to IEDB
Result Predicted by

MHC Class-II Binder

Propred Analysis

Link to Propred
Result Predicted by Propred

NetMHC-II Analysis

Link to NetMHC-II
Result Predicted by NetMHC-II

External Links

• Database of Mycobacterium tuberculosis genome sequences and related information.