Rv0041
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(New page: {{immunebox | Name =<b> leucyl-tRNA synthetase </b> |image= | width=250 |image2= |Swiss Prot = P67510 | Genbank = 887040 | PDB = | DrugBank = | chem...)
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Revision as of 11:07, 16 February 2010
Rv0041
| |
Name | |
leucyl-tRNA synthetase | |
Identifiers | |
Swiss Prot | |
Genbank | |
PDB | ? |
Chemical data | |
Formula | C19H19NO4 [1] |
Mol. wt. | 107564 Da |
Pharmacokinetic data | |
Bioavailability | ? |
Solubility | ? |
Isoelectric-Point | 4.86 |
Contents |
General
INVOLVED IN TRANSLATION MECHANISM [CATALYTIC ACTIVITY: ATP + L-leucine + tRNA(Leu) = AMP + diphosphate + L-leucyl-tRNA(Leu)].
essential gene by Himar1-based transposon mutagenesis in H37Rv and CDC1551 strains (see Sassetti et al., 2003 and Lamichhane et al., 2003) mutants available at TARGET website
Protein Sequence
>Rv0041, TB.seq 43560:46466 MW:107564 VTESPTAGPGGVPRADDADSDVPRYRYTAELAARLERTWQENWARLGTFNVPNPVGSLAPPDGAAVPDDKLFVQDMFPYP SGEGLHVGHPLGYIATDVYARYFRMVGRNVLHALGFDAFGLPAEQYAVQTGTHPRTRTEANVVNFRRQLGRLGFGHDSRR SFSTTDVDFYRWTQWIFLQIYNAWFDTTANKARPISELVAEFESGARCLDGGRDWAKLTAGERADVIDEYRLVYRADSLV NWCPGLGTVLANEEVTADGRSDRGNFPVFRKRLRQWMMRITAYADRLLDDLDVLDWPEQVKTMQRNWIGRSTGAVALFSA RAASDDGFEVDIEVFTTRPDTLFGATYLVLAPEHDLVDELVAASWPAGVNPLWTYGGGTPGEAIAAYRRAIAAKSDLERQ ESREKTGVFLGSYAINPANGEPVPIFIADYVLAGYGTGAIMAVPGHDQRDWDFARAFGLPIVEVIAGGNISESAYTGDGI LVNSDYLNGMSVPAAKRAIVDRLESAGRGRARIEFKLRDWLFARQRYWGEPFPIVYDSDGRPHALDEAALPVELPDVPDY SPVLFDPDDADSEPSPPLAKATEWVHVDLDLGDGLKPYSRDTNVMPQWAGSSWYELRYTDPHNSERFCAKENEAYWMGPR PAEHGPDDPGGVDLYVGGAEHAVLHLLYSRFWHKVLYDLGHVSSREPYRRLVNQGYIQAYAYTDARGSYVPAEQVIERGD RFVYPGPDGEVEVFQEFGKIGKSLKNSVSPDEICDAYGADTLRVYEMSMGPLEASRPWATKDVVGAYRFLQRVWRLVVDE HTGETRVADGVELDIDTLRALHRTIVGVSEDFAALRNNTATAKLIEYTNHLTKKHRDAVPRAAVEPLVQMLAPLAPHIAE ELWLRLGNTTSLAHGPFPKADAAYLVDETVEYPVQVNGKVRGRVVVAADTDEETLKAAVLTDEKVQAFLAGATPRKVIVV AGRLVNLVI
Human Homologue Blast Result
subject ids | % identity | % positives | alignment length | evalue |
sp|Q15031.2 | 29 | 44 | 936 | 2e-98 |
sp|P26640.4 | 30 | 52 | 55 | 0.004 |
sp|Q9NSE4.2 | 24 | 38 | 126 | 0.013 |
sp|P41252.2 | 23 | 40 | 236 | 0.020 |
sp|P56192.2 | 22 | 38 | 240 | 0.026 |
Alergen Protein
Link to Algpred
Non Allergen Predicted by AlgPred Server
Bacterial Toxin Prediction
Link to btxpred
No Hit Fountd by btxpred server.
Subcellular Location
Link to TBpred
Cytoplasmic
Antigens
No Hit Found in AntigenDB
No. Hit Found in IEDB
B cell Epitopes
BCEpred Analysis
Link to Bcepred
Result Predicited by
ABCpred Analysis
Link to ABCpred
Result Predicited by
IEDB Analysis
Link to IEDB
Result Predicited by
MHC Class-I Binder
nHLAPred Analysis
Link to nHLApred
Result Predicited by nHLApred
IEDB Analysis
Link to IEDB
Result Predicted by IEDB
MHC Class-II Binder
Propred Analysis
Link to Propred
Result Predicted by
NetMHC-II Analysis
Link to NetMHC-II
Result Predicted by
External Links
- Database of Mycobacterium tuberculosis genome sequences and related information.