CarboDB High molecular weight polysaccharide 1146

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Revision as of 00:00, 15 January 2001


Contents

Carbohydrate Name

High molecular weight polysaccharide

Carbohydrate Class

Miscellaneous

Source Microbe

Bacteroides fragilis NCTC 9343

Basic Structure

-3)α-D-FucpNAc4N(1-->4)α-D-GalpNAc [branched to β-D-Galf(1-->3)] (1-->3)β-D-Galp [branched via 6th and 4th positions to RPyr(2-(1-.C73


Proposed functions

Capsular polysaccharide of B. fragilis may represent a virulence factor

Antigenic Nature used to produce antibodies

whole cells of a B. fragilis NCTC 9343 enriched for expression of the EDL

Carrier Name

nil

Conjugation Method

nil

Antibodies

Mab QUBf8

Antibody type and class

IgG1

Assay System

Immunoblotting, immunofluorescence, flow cytometry

Cross-reactivity

This Mab did not cross-react with B. vulgatus, B. thetawtaomicron, B. ovatus, B. distasonis, B. gingivalis, E. coli or S. aureus. But it reacted with B. fragilis strain BE6

Proposed epitopes

N/A


Proposed Utility

N/A

Weblink

PubMed

External Links