CarboDB O-polysaccharide 1503
From DrugPedia: A Wikipedia for Drug discovery
Revision as of 00:00, 15 January 2001
Carbohydrate Name
O-polysaccharide
Carbohydrate Class
O-polysaccharide [LPS]
Source Microbe
Acinetobacter baumannii strain 24
Basic Structure
Acinetobacter LPSs consist of a polysaccharide covalently linked to a lipid component, termed lipid A, which anchors the LPS in the outer membrane. This polysaccharide is divided into the core oligosaccharide (linked to lipid A) and the O-polysaccharide or O-antigen. This type of LPS is referred to as the smooth- or S-form phenotype; the O-antigens are characteristic for a given LPS and the parental bacterial strain
Proposed functions
Since all recently investigated LPSs from Acinetobacter strains have been shown to be of the smooth phenotype, a serotyping scheme for identification of members of this genus may also be possible
Antigenic Nature used to produce antibodies
Heat killed bacteria
Carrier Name
nil
Conjugation Method
nil
Antibodies
Polysera
Antibody type and class
N/A
Assay System
Enzyme immunoassay
Cross-reactivity
The antisera cross-reacted with 13 strains A. baumannii
Proposed epitopes
N/A
Proposed Utility
This Mab can be used to detect the presence of bacterial antigens in lungs from infected animals
