PolysacDB Capsular polysaccharide 1997

From DrugPedia: A Wikipedia for Drug discovery

---

Revision as of 06:11, 8 April 2010

Contents 1 Carbohydrate Name 2 Carbohydrate Class 3 Source Microbe 4 Basic Structure 5 Proposed functions 6 Antigenic Nature used to produce antibodies 7 Carrier Name 8 Conjugation Method 9 Antibodies 10 Antibody type and class 11 Assay System 12 Cross-reactivity 13 Proposed epitopes 14 Proposed Utility 15 Weblink 16 External Links

Carbohydrate Name

Capsular polysaccharide

Carbohydrate Class

Capsular polysaccharide

Source Microbe

Streptococcus pneumoniae serotype 6B

Basic Structure

The capsular polysaccharide consists of the following residues : -2)-α-D-Galp-(1-->3)-α-D-Glcp-(1-->3)-α-L-Rhap-(1-->4)-D-Rib-ol-(5-P-

Proposed functions

N/A

Antigenic Nature used to produce antibodies

Glycoconjugates

Carrier Name

Diphtheria toxin mutant (CRM197)

Conjugation Method

N/A

Antibodies

Mab Hyp6BG7

Antibody type and class

IgG1

Assay System

Sandwich ELISA, opsonization assays

Cross-reactivity

This Mab cross-reacted with strain 6A

Proposed epitopes

N/A

Proposed Utility

This Mab had opsonophagocytic activity

Weblink

PubMed Central

External Links

• BCSDB Structural Detail

• Link to PolysacDB database