PolysacDB 125 Kda antigen 2394
From DrugPedia: A Wikipedia for Drug discovery
(Difference between revisions)
Revision as of 06:13, 8 April 2010
Carbohydrate Name
125 Kda antigen
Carbohydrate Class
Miscellaneous
Source Microbe
Streptococcus mutans OMZ175 (serotype f)
Basic Structure
N/A
Proposed functions
N/A
Antigenic Nature used to produce antibodies
Cell wall extracted antigens
Carrier Name
nil
Conjugation Method
nil
Antibodies
Mab LOSM2
Antibody type and class
IgM
Assay System
Western blotting and immunoprecipitation techniques, enzyme-linked immunosorbent assay (ELISA), and competitive ELISA
Cross-reactivity
Monoclonal antibody LOSM1 showed a quite identical reactivity with WEA from S. mutans serotypes f and b, reduced activity against WEA from serotypes c, e, and a, and weak binding to serotypes d and g
Proposed epitopes
N/A
Proposed Utility
Using this monoclonal antibody, it has been demonstrated that cross-reactivity and conservation of the specific epitopes among the various S. mutans serotypes. These Mab should be useful in studying the streptococcal surface moities
