PolysacDB Streptococcal A carbohydrate 2420
From DrugPedia: A Wikipedia for Drug discovery
(Difference between revisions)
Revision as of 06:13, 8 April 2010
Carbohydrate Name
Streptococcal A carbohydrate
Carbohydrate Class
Miscellaneous
Source Microbe
Streptococci Group A
Basic Structure
N/A
Proposed functions
This Carbohydrate is highly immunodominant
Antigenic Nature used to produce antibodies
Sera of humans having IgM myeloma
Carrier Name
nil
Conjugation Method
nil
Antibodies
Mab AC179
Antibody type and class
IgM
Assay System
solid-phase enzyme-linked immunoassay, Streptococcal agglutination assay
Cross-reactivity
ACI79 was most active in agglutinating A variant (Av) and group C streptococci
Proposed epitopes
AC179 is directed to α-linked rhamnose oligosaccharides
Proposed Utility
AC179 induced complement activation in the presence of the carbohydrate
