PolysacDB 2461
From DrugPedia: A Wikipedia for Drug discovery
(Difference between revisions)
Revision as of 06:13, 8 April 2010
Carbohydrate Name
Synthetic disaccharide abequose(1-->3)-α-rhamnose representative of Salmonella O-antigen 8
Carbohydrate Class
O-polysaccharide [LPS]
Source Microbe
Salmonella spp.
Basic Structure
Synthetic disaccharide abequose1-->3α-rhamnose
Proposed functions
N/A
Antigenic Nature used to produce antibodies
Glycoconjugate
Carrier Name
BSA
Conjugation Method
N/A
Antibodies
Antisera
Antibody type and class
N/A
Assay System
immunofluorescence and co-agglutination (COA)
Cross-reactivity
The antiserum correctly identified all 99 Salmonella serogroup C2 and C3 bacteria with O-antigen 8. No fluorescence was seen with 484 Salmonella bacteria belonging to other serogroups or 567 non-Salmonella enteric bacteria
Proposed epitopes
N/A
Proposed Utility
This antisera was used for diagnosis of Salmonella bacteria by indirect immunofluorescence (IFL) and by co-agglutination (COA) using sensitized protein A-containing staphylococci
