PolysacDB 2462

From DrugPedia: A Wikipedia for Drug discovery

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Revision as of 06:13, 8 April 2010

Contents 1 Carbohydrate Name 2 Carbohydrate Class 3 Source Microbe 4 Basic Structure 5 Proposed functions 6 Antigenic Nature used to produce antibodies 7 Carrier Name 8 Conjugation Method 9 Antibodies 10 Antibody type and class 11 Assay System 12 Cross-reactivity 13 Proposed epitopes 14 Proposed Utility 15 Weblink 16 External Links

Carbohydrate Name

6B polysaccharide [octavalent polysaccharide protein conjugate vaccine, PncT]

Carbohydrate Class

Source Microbe

Streptococcus pneumoniae serogroup 6

Basic Structure

N/A

Proposed functions

N/A

Antigenic Nature used to produce antibodies

Glycoconjugate

Carrier Name

nil

Conjugation Method

nil

Antibodies

Human Antisera

Antibody type and class

IgG

Assay System

ELISA, Opsonophagocytosis assay, in-vivo protection assay

Cross-reactivity

This antisera cross-reacts with serotype 6A

Proposed epitopes

N/A

Proposed Utility

This antisera protected mice against bacteremia and/or lung infection caused by intranasal challenge with serotypes 6B and 6A

Weblink

PubMed

External Links

• Link to PolysacDB database