20-Hydroxyecdysone

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	'''KEGG Pathway'''(C02633)		'''KEGG Pathway'''(C02633)
	*Insect hormone biosynthesis		*Insect hormone biosynthesis
-		+	{| border="1;width:100%; height:200px;style=text-align:center"
		+	|+'''List of PDB files having estriol as a Ligand:'''
		+	|-
		+	! style="background:brown; color:white" |MMDB ID
		+	! style="background:brown; color:white" |PDB ID
		+	! style="background:brown; color:white" |Reference
		+	|-
	|59627		|59627
	|2R40		|2R40

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Revision as of 05:00, 3 November 2008

Ecdysterone

Pubchem(5459840,3032482)

A steroid hormone that regulates the processes of MOLTING or ecdysis in insects. Ecdysterone is the 20-hydroxylated ECDYSONE.

KEGG Pathway(C02633)

• Insect hormone biosynthesis

List of PDB files having estriol as a Ligand:

MMDB ID	PDB ID	Reference
59627	2R40	Browning C, Martin E, Loch C, Wurtz JM, Moras D, Stote RH, Dejaegere AP, Billas IMCritical Role of Desolvation in the Binding of 20-Hydroxyecdysone to the Ecdysone ReceptorJ. Biol. Chem. v282, p.32924-32934

Toxicity:

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
mouse	LD50	intraperitoneal	6400mg/kg (6400mg/kg)		Nippon Yakurigaku Zasshi. Japanese Journal of Pharmacology. Vol. 66, Pg. 551, 1970.
mouse	LD50	oral	> 9gm/kg (9000mg/kg)		Nippon Yakurigaku Zasshi. Japanese Journal of Pharmacology. Vol. 66, Pg. 551, 1970.