Crebanine
From DrugPedia: A Wikipedia for Drug discovery
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==Description== | ==Description== | ||
RN refers to R-isomer; structure given in first source | RN refers to R-isomer; structure given in first source | ||
| + | |||
| + | Crebanine inhibits the L-type calcium current (ICa,L) and the inwardly rectifying potassium current (IK1) in guinea pig ventricular myocytes: Relevance with antiarrhythmic action. | ||
==General Properties== | ==General Properties== | ||
Current revision
| Crebanine
| |
| Systematic (IUPAC) name | |
| N/A | |
| Identifiers | |
| CAS number | ? |
| ATC code | ? |
| PubChem | |
| Chemical data | |
| Formula | C20H21NO4 |
| Mol. mass | 339.38504 |
| SMILES | & |
| Pharmacokinetic data | |
| Bioavailability | ? |
| Metabolism | ? |
| Half life | ? |
| Excretion | ? |
| Therapeutic considerations | |
| Pregnancy cat. |
? |
| Legal status | |
| Routes | ? |
[edit] Description
RN refers to R-isomer; structure given in first source
Crebanine inhibits the L-type calcium current (ICa,L) and the inwardly rectifying potassium current (IK1) in guinea pig ventricular myocytes: Relevance with antiarrhythmic action.
[edit] General Properties
*Molecular Weight
339.38504
*Molecular Formula
C20H21NO4
*IUPAC NAME
N/A
*Canonical Smiles
CN1CCC2=CC3=C(C4=C2C1CC5=C4C=CC(=C5OC)OC)OCO3
*Isomeric Smiles
N/A
*XLogP
2.8
*Topological Polar Surface Area
40.2
