PolysacDB 125 Kda antigen 2395

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Contents 1 Carbohydrate Name 2 Carbohydrate Class 3 Source Microbe 4 Basic Structure 5 Proposed functions 6 Antigenic Nature used to produce antibodies 7 Carrier Name 8 Conjugation Method 9 Antibodies 10 Antibody type and class 11 Assay System 12 Cross-reactivity 13 Proposed epitopes 14 Proposed Utility 15 Weblink 16 External Links

[edit] Carbohydrate Name

125 Kda antigen

[edit] Carbohydrate Class

Miscellaneous

[edit] Source Microbe

Streptococcus mutans OMZ175 (serotype f)

[edit] Basic Structure

N/A

[edit] Proposed functions

N/A

[edit] Antigenic Nature used to produce antibodies

Cell wall extracted antigens

[edit] Carrier Name

nil

[edit] Conjugation Method

nil

[edit] Antibodies

Mab LOSM3

[edit] Antibody type and class

IgM

[edit] Assay System

Western blotting and immunoprecipitation techniques, enzyme-linked immunosorbent assay (ELISA), and competitive ELISA

[edit] Cross-reactivity

Monoclonal antibody LOSM1 showed a quite identical reactivity with WEA from S. mutans serotypes f and b, reduced activity against WEA from serotypes c, e, and a, and weak binding to serotypes d and g

[edit] Proposed epitopes

N/A

[edit] Proposed Utility

Using this monoclonal antibody, it has been demonstrated that cross-reactivity and conservation of the specific epitopes among the various S. mutans serotypes. These Mab should be useful in studying the streptococcal surface moities

[edit] Weblink

PubMed Central

[edit] External Links

• Link to PolysacDB database