20-Hydroxyecdysone

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Ecdysterone

Pubchem(5459840,3032482)

A steroid hormone that regulates the processes of MOLTING or ecdysis in insects. Ecdysterone is the 20-hydroxylated ECDYSONE.

KEGG Pathway(C02633)

  • Insect hormone biosynthesis
List of PDB files having estriol as a Ligand:
MMDB ID PDB ID Reference
59627 2R40 Browning C, Martin E, Loch C, Wurtz JM, Moras D, Stote RH, Dejaegere AP, Billas IMCritical Role of Desolvation in the Binding of 20-Hydroxyecdysone to the Ecdysone ReceptorJ. Biol. Chem. v282, p.32924-32934
Toxicity:
Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intraperitoneal 6400mg/kg (6400mg/kg) Nippon Yakurigaku Zasshi. Japanese Journal of Pharmacology. Vol. 66, Pg. 551, 1970.
mouse LD50 oral > 9gm/kg (9000mg/kg) Nippon Yakurigaku Zasshi. Japanese Journal of Pharmacology. Vol. 66, Pg. 551, 1970.