Glucagon receptor precursor
From DrugPedia: A Wikipedia for Drug discovery
Contents |
Source Organism
Rattus norvegicus (Rat).
Taxomomy
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Rattus.
Subcellular Localization
Cell membrane; multi-pass membrane protein.
Developmental Stage
Similarity
Belongs to the G-protein coupled receptor 2 family.
Post translational Modification
Function
This is a receptor for glucagon which plays a central role in regulating the level of blood glucose by controlling the rate of hepatic glucose production and insulin secretion. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and also a phosphatidylinositol-calcium second messenger system.
