Testosterone

From DrugPedia: A Wikipedia for Drug discovery

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Contents [hide] 1 Description 2 General Properties 3 PhysioChemical Properties 4 External Links

Description

A potent androgenic steroid and major product secreted by the LEYDIG CELLS of the TESTIS. Its production is stimulated by LUTEINIZING HORMONE from the PITUITARY GLAND. In turn, testosterone exerts feedback control of the pituitary LH and FSH secretion. Depending on the tissues, testosterone can be further converted to DIHYDROTESTOSTERONE or ESTRADIOL.

General Properties

*Molecular Weight

288.42

*Molecular Formula

C₁₉H₂₈O₂

*IUPAC NAME

(8R,9S,10R,13S,14S,17S)-17-hydroxy-10,13-dimethyl-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-one

*Canonical Smiles

CC12CCC3C(C1CCC2O)CCC4=CC(=O)CCC34C

*Isomeric Smiles

C[C@]12CC[C@H]3[C@H]([C@@H]1CC[C@@H]2O)CCC4=CC(=O)CC[C@]34C

PhysioChemical Properties

*Melting Point

155(EXP)

*LogP

3.32(EXP)

*Water Solubility

23.4(EXP) at 25C

External Links

• [1]Pubchem
• [2]]1I37,[[3]]1I38,[[4]]1I9J,[[5]]1J96,[[6]]1Q13,[[7]]1VPO,[[8]]2Q7I,[[9]]2Q7J,[[10]]2Q7K,[[11]]2Q7L,[[12]]1AFS,
• [13]KEGG Compound
• [14]KEGG Drug
• [15]Human Metabolome DataBase
• [16]Drugbank

Categories:Hormones