Genistein

From DrugPedia: A Wikipedia for Drug discovery

Contents 1 Description 2 General Properties 3 PhysioChemical Properties 4 External Links

Description

An isoflavonoid derived from soy products. It inhibits PROTEIN-TYROSINE KINASE and topoisomerase-II (DNA TOPOISOMERASES, TYPE II); activity and is used as an antineoplastic and antitumor agent. Experimentally, it has been shown to induce G2 PHASE arrest in human and murine cell lines and inhibits PROTEIN-TYROSINE KINASE.

General Properties

*Molecular Weight

270.24

*Molecular Formula

C₁₅H₁₀O₅

*IUPAC NAME

5,7-dihydroxy-3-(4-hydroxyphenyl)chromen-4-one

*Canonical Smiles

C1=CC(=CC=C1C2=COC3=CC(=CC(=C3C2=O)O)O)O

*Isomeric Smiles

PhysioChemical Properties

*Melting Point

301.5(EXP)

*LogP

2.84(EST)

*Water Solubility

External Links

• [1]Pubchem
• [2]KEGG Compound
• [3]Human Metabolome DataBase
• [4]Drugbank

Categories:Hormones