Triiodothyronine

From DrugPedia: A Wikipedia for Drug discovery

Contents 1 Description 2 General Properties 3 PhysioChemical Properties 4 External Links

Description

A T3 thyroid hormone normally synthesized and secreted by the thyroid gland in much smaller quantities than thyroxine (T4). Most T3 is derived from peripheral monodeiodination of T4 at the 5' position of the outer ring of the iodothyronine nucleus. The hormone finally delivered and used by the tissues is mainly T3.

General Properties

*Molecular Weight

650.97

*Molecular Formula

C₁₅H₁₂I₃NO₄

*IUPAC NAME

(2S)-2-amino-3-[4-(4-hydroxy-3-iodophenoxy)-3,5-diiodophenyl]propanoicacid

*Canonical Smiles

C1=CC(=C(C=C1OC2=C(C=C(C=C2I)CC(C(=O)O)N)I)I)O

*Isomeric Smiles

C1=CC(=C(C=C1OC2=C(C=C(C=C2I)C[C@@H](C(=O)O)N)I)I)O

PhysioChemical Properties

*Melting Point

236.5(EXP)

*LogP

2.96(EST)

*Water Solubility

3.96(EXP) at 37C

External Links

• [1]Pubchem
• [2]]1BSX,[[3]]1SN5,[[4]]1XZX,[[5]]2H6W,[[6]]2H77,[[7]]2H79,[[8]]2PIV,[[9]]2PIW,
• [10]KEGG Compound
• [11]Human Metabolome DataBase
• [12]Drugbank

Categories:Hormones