List of proteins specific to Mycobacterium

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This is a manually curated list of Mtu proteins that have no near orthologs outside the Mycobacterium genus. We define orthologs as in [1] and use the OMAbrowser manually to find such proteins. The list should give the UniProt external link, named with the UniProt Code, followed by at least the ORF name, better the ordered locus name. Finally, a possible function should be given in parentheses.

name/locus/orf link poss. function
lprN, orf TBCG_03429 UniProt A2VPR7 virulence factor, MCE-family lipoprotein
mce4A, orf TBCG_03433 UniProt A2VPS1 virulence factor, MCE-family protein
mce4C, orf TBCG_03431 UniProt A2VPR9 virulence factor, MCE-family protein
cyp144, Rv1777, MT1827 UniProt O33180 cytochrome P450
mbtD, orf TBCG_02323 UniProt A2VKA7 polyketide synthetase mbtD
orf TBCG_02994 UniProt A2VNM4 unchar. / tetR-Domain
mmpL11, Rv0202c, MT0212 UniProt P65374 unchar. / membrane protein / sterol sensing?
Rv0008c, MT0010 UniProt P71577 unchar. / membrane protein
orf TBCG_03529 UniProt A2VLZ2 unchar. / membrane protein, ala-,arg-,pro-rich