List of proteins specific to Mycobacterium
From DrugPedia: A Wikipedia for Drug discovery
This is a manually curated list of Mtu proteins that have no near orthologs outside the Mycobacterium genus. We define orthologs as in [1] and use the OMAbrowser manually to find such proteins. The list should give the UniProt external link, named with the UniProt Code, followed by at least the ORF name, better the ordered locus name. Finally, a possible function should be given in parentheses.
| name/locus/orf | link | poss. function |
|---|---|---|
| lprN, orf TBCG_03429 | UniProt A2VPR7 | virulence factor, MCE-family lipoprotein |
| lppI, Rv2046, orf TBCG_01999 | UniProt A2VJF4 | lipoprotein |
| mce4A, orf TBCG_03433 | UniProt A2VPS1 | virulence factor, MCE-family protein |
| mce4C, orf TBCG_03431 | UniProt A2VPR9 | virulence factor, MCE-family protein |
| cyp144, Rv1777, MT1827 | UniProt O33180 | cytochrome P450 |
| mbtD, orf TBCG_02323 | UniProt A2VKA7 | polyketide synthetase mbtD |
| MT3144, orf TBCG_02994 | UniProt A2VNM4 | unchar. / tetR domain |
| Rv0518, orf TBCG_00512 | UniProt A2VFK3 | unchar. / lipase domain, exported? |
| Rv0516c, MT0537 | UniProt A2VFK1 | unchar. / Sulphate Transporter and AntiSigma factor antagonist-domain |
| mmpL11, Rv0202c, MT0212 | UniProt P65374 | unchar. / membrane protein / sterol sensing? |
| Rv2668 | UniProt P71965 | unchar. / ala-,val-rich, exported |
| Rv3604c, orf TBCG_03529 | UniProt A2VLZ2 | unchar. / membrane protein, ala-,arg-,pro-rich |
| Rv0008c, MT0010 | UniProt P71577 | unchar. / membrane protein |
| MT1164 | UniProt Q7D8S7 | unchar. / membrane protein |
| Rv0381c, orf TBHG_00376 | UniProt A4KE70 | unchar. / membrane protein |
| Rv0680c, orf TBCG_00670 | UniProt A2VFY9 | unchar. / membrane protein |
| Rv0686, orf TBCG_00676 | UniProt A2VFZ4 | unchar. / membrane protein |
| Rv0314c, orf TBCG_00309 | UniProt A2VF18 | unchar. / membrane protein |
| Rv2799, orf TBCG_02735 | UniProt A2VLD2 | unchar. / membrane protein |
| Rv3492c, orf TBCG_03426 | UniProt A2VPR4 | MCE associated |
| UsfY, Rv3288c | UniProt A4KLI4 | unchar. |
| Rv1489, orf TBHG_01468 | UniProt A4KH34 | unchar. |
| Rv1598c, orf TBCG_01552 | UniProt A2VI89 | unchar. |
| Rv3440c, orf TBCG_03379 | UniProt A2VPM2 | unchar. |
| Rv0209 | [2] | unchar. |
