From DrugPedia: A Wikipedia for Drug discovery

Rv0798c
Name
cfp29
Identifiers
Swiss Prot	O07181
Genbank	885460
PDB	?
Chemical data
Formula	C17H16ClNO4 [1]
Mol. wt.	28831 Da
Pharmacokinetic data
Bioavailability	?
Solubility	?
Isoelectric-Point	4.67

Contents 1 General 1.1 Protein Sequence 2 Human Homologue Blast Result 3 Alergen Protein 4 Bacterial Toxin Prediction 5 Subcellular Location 6 Antigens 6.1 B cell Epitopes 6.1.1 BCEpred Analysis 6.1.2 ABCpred Analysis 6.1.3 IEDB Analysis 7 MHC Class-I Binder 7.1 nHLAPred Analysis 7.2 IEDB Analysis 8 MHC Class-II Binder 8.1 Propred Analysis 8.2 NetMHC-II Analysis 9 External Links

General

UNKNOWN FUNCTION. SUPPOSED RELEASED FROM THE ENVELOPE TO THE OUTSIDE DURING GROWTH. Product: similar to bacteriocins , 29KDa ANTIGEN CFP29

essential gene by Himar1-based transposon mutagenesis in H37Rv strain (see Sassetti et al., 2003) non essential gene by Himar1-based transposon mutagenesis in CDC1551 strain (see Lamichhane et al., 2003) mutants available at TARGET website

Protein Sequence

>Rv0798c, TB.seq 891473:892267 MW:28831 MNNLYRDLAPVTEAAWAEIELEAARTFKRHIAGRRVVDVSDPGGPVTAAVSTGRLIDVKAPTNGVIAHLRASKPLVRLRV PFTLSRNEIDDVERGSKDSDWEPVKEAAKKLAFVEDRTIFEGYSAASIEGIRSASSNPALTLPEDPREIPDVISQALSEL RLAGVDGPYSVLLSADVYTKVSETSDHGYPIREHLNRLVDGDIIWAPAIDGAFVLTTRGGDFDLQLGTDVAIGYASHDTD TVRLYLQETLTFLCYTAEASVALSH

Human Homologue Blast Result

subject ids	% identity	% positives	alignment length	evalue
sp|O60645.2	26	47	71	3.5
sp|O95613.3	32	42	80	4.2
sp|Q9ULV5.1	45	54	35	4.9
sp|Q6ZW49.1	30	51	66	5.3
sp|Q15080.2	31	51	54	8.5

Alergen Protein

Link to Algpred
Non Allergen Predicted by AlgPred Server

Bacterial Toxin Prediction

Link to btxpred
No Hit Fountd by btxpred server.

Subcellular Location

Link to TBpred
Cytoplasmic

Antigens

No Hit Found in AntigenDB
No. Hit Found in IEDB

B cell Epitopes

BCEpred Analysis

Link to Bcepred
Result Predicited by

ABCpred Analysis

Link to ABCpred
Result Predicited by

IEDB Analysis

Link to IEDB
Result Predicited by

MHC Class-I Binder

nHLAPred Analysis

Link to nHLApred
Result Predicited by nHLApred

IEDB Analysis

Link to IEDB
Result Predicted by IEDB

MHC Class-II Binder

Propred Analysis

Link to Propred
Result Predicted by

NetMHC-II Analysis

Link to NetMHC-II
Result Predicted by

External Links

• Database of Mycobacterium tuberculosis genome sequences and related information.