Rv3002c
From DrugPedia: A Wikipedia for Drug discovery
| Rv3002c
| |
| Name | |
| acetolactate synthase 3 regulatory subunit (ilvH ) | |
| Identifiers | |
| Swiss Prot | |
| Genbank | |
| PDB | ? |
| Chemical data | |
| Formula | C16H15Cl2NO2 [1] |
| Mol. wt. | 18188 Da |
| Pharmacokinetic data | |
| Bioavailability | ? |
| Solubility | ? |
| Isoelectric-Point | 8.5 |
Contents |
General
INVOLVED IN VALINE AND ISOLEUCINE BIOSYNTHESIS (AT THE FIRST STEP) [CATALYTIC ACTIVITY: 2-ACETOLACTATE + CO(2) = 2-PYRUVATE].
Essential gene by Himar1-based transposon mutagenesis in H37Rv strain (see Sassetti et al., 2003) mutants available at TARGET website
Protein Sequence
>Rv3002c, TB.seq 3360624:3361127 MW:18188 MSPKTHTLSVLVEDKPGVLARVAALFSRRGFNIESLAVGATECKDRSRMTIVVSAEDTPLEQITKQLNKLINVIKIVEQD DEHSVSRELALIKVQADAGSRSQVIEAVNLFRANVIDVSPESLTVEATGNRGKLEALLRVLEPFGIREIAQSGMVSLSRG PRGIGTAK
Human Homologue Blast Result
| subject ids | % identity | % positives | alignment length | evalue |
| sp|Q9Y2X3.1 | 62 | 75 | 24 | 0.25 |
| sp|Q9H7B4.4 | 27 | 48 | 90 | 1.6 |
| sp|Q8IZD2.1 | 22 | 37 | 125 | 1.9 |
| sp|Q9UM54.4 | 42 | 71 | 2.5 | 2.0 |
| sp|P54317.1 | 28 | 63 | 38 | 2.9 |
Alergen Protein
Link to Algpred
Non Allergen Predicted by AlgPred Server
Bacterial Toxin Prediction
Link to btxpred
No Hit Fountd by btxpred server.
Subcellular Location
Link to TBpred
Integral Membrane
Antigens
No Hit Found in AntigenDB
No. Hit Found in IEDB
B cell Epitopes
BCEpred Analysis
Link to Bcepred
Result Predicited by
ABCpred Analysis
Link to ABCpred
Result Predicited by
IEDB Analysis
Link to IEDB
Result Predicited by
MHC Class-I Binder
nHLAPred Analysis
Link to nHLApred
Result Predicited by nHLApred
IEDB Analysis
Link to IEDB
Result Predicted by IEDB
MHC Class-II Binder
Propred Analysis
Link to Propred
Result Predicted by
NetMHC-II Analysis
Link to NetMHC-II
Result Predicted by
External Links
- Database of Mycobacterium tuberculosis genome sequences and related information.
