CarboDB High molecular weight polysaccharide 1146

From DrugPedia: A Wikipedia for Drug discovery

Contents 1 Carbohydrate Name 2 Carbohydrate Class 3 Source Microbe 4 Basic Structure 5 Proposed functions 6 Antigenic Nature used to produce antibodies 7 Carrier Name 8 Conjugation Method 9 Antibodies 10 Antibody type and class 11 Assay System 12 Cross-reactivity 13 Proposed epitopes 14 Proposed Utility 15 Weblink 16 External Links

[edit] Carbohydrate Name

High molecular weight polysaccharide

[edit] Carbohydrate Class

Miscellaneous

[edit] Source Microbe

Bacteroides fragilis NCTC 9343

[edit] Basic Structure

-3)α-D-FucpNAc4N(1-->4)α-D-GalpNAc [branched to β-D-Galf(1-->3)] (1-->3)β-D-Galp [branched via 6th and 4th positions to RPyr(2-(1-.C73

[edit] Proposed functions

Capsular polysaccharide of B. fragilis may represent a virulence factor

[edit] Antigenic Nature used to produce antibodies

whole cells of a B. fragilis NCTC 9343 enriched for expression of the EDL

[edit] Carrier Name

nil

[edit] Conjugation Method

nil

[edit] Antibodies

Mab QUBf8

[edit] Antibody type and class

IgG1

[edit] Assay System

Immunoblotting, immunofluorescence, flow cytometry

[edit] Cross-reactivity

This Mab did not cross-react with B. vulgatus, B. thetawtaomicron, B. ovatus, B. distasonis, B. gingivalis, E. coli or S. aureus. But it reacted with B. fragilis strain BE6

[edit] Proposed epitopes

N/A

[edit] Proposed Utility

N/A

[edit] Weblink

PubMed

[edit] External Links

• Link to CarboDB database