CarboDB Lipopolysaccharide 1365

From DrugPedia: A Wikipedia for Drug discovery

Contents 1 Carbohydrate Name 2 Carbohydrate Class 3 Source Microbe 4 Basic Structure 5 Proposed functions 6 Antigenic Nature used to produce antibodies 7 Carrier Name 8 Conjugation Method 9 Antibodies 10 Antibody type and class 11 Assay System 12 Cross-reactivity 13 Proposed epitopes 14 Proposed Utility 15 Weblink 16 External Links

[edit] Carbohydrate Name

Lipopolysaccharide

[edit] Carbohydrate Class

Lipopolysaccharide

[edit] Source Microbe

Chlamydia pneumoniae TW-183

[edit] Basic Structure

It has the core lipid A moiety and 3-deoxy-D-manno-oct-2-ulosonic acid (Kdo) core but lacks the distal O-polysaccharide region

[edit] Proposed functions

N/A

[edit] Antigenic Nature used to produce antibodies

Whole cells

[edit] Carrier Name

nil

[edit] Conjugation Method

nil

[edit] Antibodies

Mab CP-33

[edit] Antibody type and class

IgG2b

[edit] Assay System

N/A

[edit] Cross-reactivity

This Mab recognized the LPSs of C. pneumoniae, Chlamydia trachomatis, and Chlamydia psittaci but did not react with 15 genera of gram-negative and gram-positive bacteria and Candida albicans

[edit] Proposed epitopes

This Mab recognizes a trisaccharide epitope αKdo(2-->8) αKdo(2-->4)αKdo

[edit] Proposed Utility

This Mab neutralizes both in vitro and in vivo the infectivity of C. pneumoniae

[edit] Weblink

PubMed Central

[edit] External Links

• Link to CarboDB database