CarboDB Capsular polysaccharide 1464
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Revision as of 00:00, 15 January 2001 by Special:Contributions/ (Talk)
Carbohydrate Name
Capsular polysaccharide
Carbohydrate Class
Capsular polysaccharide
Source Microbe
Enterococcus faecalis 12030
Basic Structure
Glycerol teichoic acid-like molecules with a carbohydrate backbone structure of 6-α-D-glucose- 1-->2 glycerol-3-PO4 with substitution on carbon 2 of the glucose with an α-2-1-D-glucose residue
Proposed functions
These polysaccharides are major virulence factors
Antigenic Nature used to produce antibodies
gentamicin-killed Enterococcus faecalis strains
Carrier Name
nil
Conjugation Method
nil
Antibodies
Polysera
Antibody type and class
N/A
Assay System
Opsonophagocytic assay, immunoelectron microscopy
Cross-reactivity
This antisera reacted with the homologous strain (12030) and mediated opsonic killing of 33% of all strains tested. In addition, this serum killed two (28%) of seven vancomycin-resistant Enterococcus faecium strains
Proposed epitopes
N/A
Proposed Utility
This antisera was opsonophagcytic
