CarboDB Unknown carbohydrate 1542
From DrugPedia: A Wikipedia for Drug discovery
Revision as of 00:00, 15 January 2001 by Special:Contributions/ (Talk)
Carbohydrate Name
Unknown carbohydrate
Carbohydrate Class
Miscellaneous
Source Microbe
Leishmania tropica (LRC-L137)
Basic Structure
N/A
Proposed functions
N/A
Antigenic Nature used to produce antibodies
L. tropica (LRC-L137) promastigotes
Carrier Name
nil
Conjugation Method
nil
Antibodies
Mab L-5-85
Antibody type and class
IgG2a
Assay System
solid-phase radioimmunoassay, Indirect fluorescent antibody test
Cross-reactivity
This Mab cross-reacted with 4 strains of L. tropica - L137, L287, L251, L38. It also cross-reacted with L. enriettii L144 strain
Proposed epitopes
N/A
Proposed Utility
This Mab would allow the study of the origin and the location of the Leishmania spp. antigens on the macrophage membrane as well as the characterization of these antigens in terms of their relationship to host histocompatibility antigens involved in antigen presentation
