PolysacDB Antigen 5 1756
From DrugPedia: A Wikipedia for Drug discovery
Carbohydrate Name
Antigen 5
Carbohydrate Class
Miscellaneous
Source Microbe
Mycobacterium tuberculosis
Basic Structure
Antigen 5 is a well known 35,000-dalton glycoprotein of Mycobacteriun tuberculosis
Proposed functions
N/A
Antigenic Nature used to produce antibodies
M. tuberculosis culture filtrate
Carrier Name
nil
Conjugation Method
nil
Antibodies
Mab TB-C-11
Antibody type and class
IgM
Assay System
ELISA, immunoabsorbent affinity chromatography
Cross-reactivity
This Mab is highly cross-reactive and cross-reacted with M. kansasii, M. gordonae, M. scrofulaceum and M. intracellulare and also cross-reacted with antigen 6 from Mycobacterium tuberculosis
Proposed epitopes
Arabinomannan and arabinogalactan residues seemed to be a part of the epitope
Proposed Utility
This Mab would allow the purification of important mycobacterial antigens antigens