PolysacDB Antigen 5 1757

From DrugPedia: A Wikipedia for Drug discovery

Contents 1 Carbohydrate Name 2 Carbohydrate Class 3 Source Microbe 4 Basic Structure 5 Proposed functions 6 Antigenic Nature used to produce antibodies 7 Carrier Name 8 Conjugation Method 9 Antibodies 10 Antibody type and class 11 Assay System 12 Cross-reactivity 13 Proposed epitopes 14 Proposed Utility 15 Weblink 16 External Links

[edit] Carbohydrate Name

Antigen 5

[edit] Carbohydrate Class

Miscellaneous

[edit] Source Microbe

Mycobacterium tuberculosis

[edit] Basic Structure

Antigen 5 is a well known 35,000-dalton glycoprotein of Mycobacteriun tuberculosis

[edit] Proposed functions

N/A

[edit] Antigenic Nature used to produce antibodies

M. tuberculosis culture filtrate

[edit] Carrier Name

nil

[edit] Conjugation Method

nil

[edit] Antibodies

Mab TB-C-12

[edit] Antibody type and class

IgM

[edit] Assay System

ELISA, immunoabsorbent affinity chromatography

[edit] Cross-reactivity

This Mab is highly cross-reactive and cross-reacted with M. kansasii, M. gordonae, M. scrofulaceum and M. intracellulare and also cross-reacted with antigen 6 from Mycobacterium tuberculosis

[edit] Proposed epitopes

Arabinomannan and arabinogalactan residues seemed to be a part of the epitope

[edit] Proposed Utility

This Mab would allow the purification of important mycobacterial antigens antigens

[edit] Weblink

PubMed Central

[edit] External Links

• Link to PolysacDB database