PolysacDB Band 1 glycolipid antigen 1896

From DrugPedia: A Wikipedia for Drug discovery

Contents 1 Carbohydrate Name 2 Carbohydrate Class 3 Source Microbe 4 Basic Structure 5 Proposed functions 6 Antigenic Nature used to produce antibodies 7 Carrier Name 8 Conjugation Method 9 Antibodies 10 Antibody type and class 11 Assay System 12 Cross-reactivity 13 Proposed epitopes 14 Proposed Utility 15 Weblink 16 External Links

Carbohydrate Name

Band 1 glycolipid antigen

Carbohydrate Class

Miscellaneous

Source Microbe

Paracoccidiodes brasiliensis

Basic Structure

The structure of glycolipid antigen is Galfβ1->6(Manpα1-->3)Manpβ1-->2Ins

Proposed functions

N/A

Antigenic Nature used to produce antibodies

Whole cells

Carrier Name

nil

Conjugation Method

nil

Antibodies

Mab MEST1

Antibody type and class

IgG3

Assay System

High performance thin layer chromatography immunostaining, solid phase radioimmunoassay

Cross-reactivity

This Mab cross-reacted with promastigotes of Leishmania major and epimastigotes of Trypanosoma cruzi

Proposed epitopes

Terminal residue of β-D-galactofuranose of Band 1 seems to be a part of the epitope

Proposed Utility

MAb MEST-1 can be a valuable tool in studies of biological role of galactofuranose residues

Weblink

PubMed

External Links

• IEDB Epitopic Detail

• Link to PolysacDB database