PolysacDB Complex oligosaccharide 1914

From DrugPedia: A Wikipedia for Drug discovery

Contents 1 Carbohydrate Name 2 Carbohydrate Class 3 Source Microbe 4 Basic Structure 5 Proposed functions 6 Antigenic Nature used to produce antibodies 7 Carrier Name 8 Conjugation Method 9 Antibodies 10 Antibody type and class 11 Assay System 12 Cross-reactivity 13 Proposed epitopes 14 Proposed Utility 15 Weblink 16 External Links

Carbohydrate Name

Complex oligosaccharide

Carbohydrate Class

Miscellaneous

Source Microbe

Plasmodium yoelii

Basic Structure

N/A

Proposed functions

N/A

Antigenic Nature used to produce antibodies

Aedes aegypti midgut extracts

Carrier Name

nil

Conjugation Method

nil

Antibodies

Mab MG96

Antibody type and class

IgG1

Assay System

ELISA, immunoblotting, immunoelectron microscopy and immunofluorescence

Cross-reactivity

This Mab shows cross-reactivity with midgut antigens from Anopheles stephensi and Anopheles gambiae

Proposed epitopes

O-linked carbohydrates seemed to be the part of the reactive epitope

Proposed Utility

Mab MG96 Completely Blocks Plasmodium yoelii Development in Anopheles stephensi

Weblink

PubMed Central

External Links

• Link to PolysacDB database