PolysacDB Complex oligosaccharide 1914

From DrugPedia: A Wikipedia for Drug discovery

Contents 1 Carbohydrate Name 2 Carbohydrate Class 3 Source Microbe 4 Basic Structure 5 Proposed functions 6 Antigenic Nature used to produce antibodies 7 Carrier Name 8 Conjugation Method 9 Antibodies 10 Antibody type and class 11 Assay System 12 Cross-reactivity 13 Proposed epitopes 14 Proposed Utility 15 Weblink 16 External Links

[edit] Carbohydrate Name

Complex oligosaccharide

[edit] Carbohydrate Class

Miscellaneous

[edit] Source Microbe

Plasmodium yoelii

[edit] Basic Structure

N/A

[edit] Proposed functions

N/A

[edit] Antigenic Nature used to produce antibodies

Aedes aegypti midgut extracts

[edit] Carrier Name

nil

[edit] Conjugation Method

nil

[edit] Antibodies

Mab MG96

[edit] Antibody type and class

IgG1

[edit] Assay System

ELISA, immunoblotting, immunoelectron microscopy and immunofluorescence

[edit] Cross-reactivity

This Mab shows cross-reactivity with midgut antigens from Anopheles stephensi and Anopheles gambiae

[edit] Proposed epitopes

O-linked carbohydrates seemed to be the part of the reactive epitope

[edit] Proposed Utility

Mab MG96 Completely Blocks Plasmodium yoelii Development in Anopheles stephensi

[edit] Weblink

PubMed Central

[edit] External Links

• Link to PolysacDB database