20-Hydroxyecdysone

From DrugPedia: A Wikipedia for Drug discovery

Revision as of 04:58, 3 November 2008 by Deepak (Talk | contribs)
(diff) ←Older revision | Current revision (diff) | Newer revision→ (diff)
Jump to: navigation, search

Ecdysterone

Pubchem(5459840,3032482)

A steroid hormone that regulates the processes of MOLTING or ecdysis in insects. Ecdysterone is the 20-hydroxylated ECDYSONE.

KEGG Pathway(C02633)

  • Insect hormone biosynthesis

|59627 |2R40 |Browning C, Martin E, Loch C, Wurtz JM, Moras D, Stote RH, Dejaegere AP, Billas IMCritical Role of Desolvation in the Binding of 20-Hydroxyecdysone to the Ecdysone ReceptorJ. Biol. Chem. v282, p.32924-32934 |- |}

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source |mouse |LD50 |intraperitoneal |6400mg/kg (6400mg/kg) |Nippon Yakurigaku Zasshi. Japanese Journal of Pharmacology. Vol. 66, Pg. 551, 1970. |- |mouse |LD50 |oral |> 9gm/kg (9000mg/kg) |Nippon Yakurigaku Zasshi. Japanese Journal of Pharmacology. Vol. 66, Pg. 551, 1970. |- |}

Retrieved from "http://140949.jxltd.asia/drugpedia/index.php/20-Hydroxyecdysone"