Ethinyl Estradiol

From DrugPedia: A Wikipedia for Drug discovery

Contents 1 Description 2 General Properties 3 PhysioChemical Properties 4 External Links

Description

A semisynthetic alkylated ESTRADIOL with a 17-alpha-ethinyl substitution. It has high estrogenic potency when administered orally, and is often used as the estrogenic component in ORAL CONTRACEPTIVES.

General Properties

*Molecular Weight

296.4

*Molecular Formula

C₂₀H₂₄O₂

*IUPAC NAME

(8R,9S,13S,14S,17R)-17-ethynyl-13-methyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthrene-3,17-diol

*Canonical Smiles

CC12CCC3C(C1CCC2(C#C)O)CCC4=C3C=CC(=C4)O

*Isomeric Smiles

C[C@]12CC[C@H]3[C@H]([C@@H]1CC[C@]2(C#C)O)CCC4=C3C=CC(=C4)O

PhysioChemical Properties

*Melting Point

183(EXP)

*LogP

3.67(EXP)

*Water Solubility

11.3(EXP) at 27C

External Links

• [1]Pubchem
• [2]KEGG Compound
• [3]KEGG Drug
• [4]Drugbank

Categories:Hormones