Triamcinolone

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Contents [hide] 1 Description 2 General Properties 3 PhysioChemical Properties 4 External Links

Description

A glucocorticoid given, as the free alcohol or in esterified form, orally, intramuscularly, by local injection, by inhalation, or applied topically in the management of various disorders in which corticosteroids are indicated. (From Martindale, The Extra Pharmacopoeia, 30th ed, p739)

General Properties

*Molecular Weight

394.43

*Molecular Formula

C₂₁H₂₇FO₆

*IUPAC NAME

(8S,9R,10S,11S,13S,14S,16R,17S)-9-fluoro-11,16,17-trihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one

*Canonical Smiles

CC12CC(C3(C(C1CC(C2(C(=O)CO)O)O)CCC4=CC(=O)C=CC43C)F)O

*Isomeric Smiles

C[C@]12C[C@@H]([C@]3([C@H]([C@@H]1C[C@H]([C@@]2(C(=O)CO)O)O)CCC4=CC(=O)C=C[C@@]43C)F)O

PhysioChemical Properties

*Melting Point

270(EXP)

*LogP

1.16(EXP)

*Water Solubility

80(EXP) at 25C

External Links

• [1]Pubchem
• [2]KEGG Drug
• [3]Drugbank

Categories:Hormones