Thromboxane A2

From DrugPedia: A Wikipedia for Drug discovery

Contents 1 Description 2 General Properties 3 PhysioChemical Properties 4 External Links

Description

An unstable intermediate between the prostaglandin endoperoxides and thromboxane B2. The compound has a bicyclic oxaneoxetane structure. It is a potent inducer of platelet aggregation and causes vasoconstriction. It is the principal component of rabbit aorta contracting substance (RCS).

General Properties

*Molecular Weight

352.47

*Molecular Formula

C₂₀H₃₂O₅

*IUPAC NAME

(Z)-7-[(1S,2S,3R,5S)-3-[(E,3S)-3-hydroxyoct-1-enyl]-4,7-dioxabicyclo[3.1.1]heptan-2-yl]hept-5-enoic acid

*Canonical Smiles

CCCCCC(C=CC1C(C2CC(O2)O1)CC=CCCCC(=O)O)O

*Isomeric Smiles

CCCCC[C@@H](C=C[C@@H]1[C@H]([C@@H]2C[C@@H](O2)O1)CC=C/CCCC(=O)O)O

PhysioChemical Properties

*Melting Point

*LogP

*Water Solubility

External Links

• [1]Pubchem
• [2]KEGG Compound
• [3]Human Metabolome DataBase

Categories:Hormones