PreClinical Trial

From DrugPedia: A Wikipedia for Drug discovery

Preclinical Testing:

The compound is tested for safety and efficacy in laboratory and animal studies.Before testing compound on humans in clinical trials, scientists must show that the compound do not present an unacceptable level of risk, given the expected therapeutic benefit.The twenty or so perfected compounds are evaluated both in vitro and in vivo. Of these, between one and five will have the characteristics required for Phase-I clinical studies.This process will take about 4-6 months.

Preclinical Testing Involves:

1. Pharmacology
2. Toxicology
3. Preformulation
4. Formulation
5. Analytical
6. Pharmacokinetics