Glaucine

From DrugPedia: A Wikipedia for Drug discovery

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[edit] Description

RN given refers to (+-)-isomer

Glaucine is an alkaloid found in several different plant species such as Glaucium flavum, Glaucium oxylobum, Croton lechleri and Corydalis yanhusuo. It has bronchodilator and antiinflammatory effects, acting as a PDE4 inhibitor and calcium channel blocker, and is used medically as an antitussive in some countries. Glaucine may produce side effects such as sedation, fatigue, and a hallucinogenic effect characterised by colourful visual images, and has recently been detected as a novel recreational drug.

[edit] General Properties

*Molecular Weight

355.4275

*Molecular Formula

C₂₁H₂₅NO₄

*IUPAC NAME

N/A

*Canonical Smiles

CN1CCC2=CC(=C(C3=C2C1CC4=CC(=C(C=C43)OC)OC)OC)OC

*Isomeric Smiles

N/A

*XLogP

2.6

*Topological Polar Surface Area

40.2

[edit] External Links

• Pubchem

Link to BIAdb Database