Coclaurine

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[edit] Description

Coclaurine competitively antagonize the uterine muscular contractions induced by acetylcholine and calcium. The antagonism is more efficient for the alkaloid coclaurine which is even stronger than papaverine.

[edit] General Properties

*Molecular Weight

285.33766

*Molecular Formula

C₁₇H₁₉NO₃

*IUPAC NAME

(1S)-1-[(4-hydroxyphenyl)methyl]-6-methoxy-1,2,3,4-tetrahydroisoquinolin-7-ol

*Canonical Smiles

COC1=C(C=C2C(NCCC2=C1)CC3=CC=C(C=C3)O)O

*Isomeric Smiles

COC1=C(C=C2[C@@H](NCCC2=C1)CC3=CC=C(C=C3)O)O

*XLogP

2

*Topological Polar Surface Area

61.7

[edit] External Links

• Pubchem

Link to BIAdb Database